Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Notes
Sparassis crispa (Hanabiratake) Ameliorates Skin Conditions in Rats and Humans
Takashi KIMURAMamiko HASHIMOTOMunenori YAMADAYoshihiro NISHIKAWA
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JOURNAL FREE ACCESS

2013 Volume 77 Issue 9 Pages 1961-1963

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Abstract

Sparassis crispa (SC) is an edible mushroom with various medicinal properties. In this study, we investigated to determine whether SC would affect skin conditions in rats and humans. Oral administration of SC increased both turnover of the stratum corneum and dermal soluble collagen content in collagen synthetic activity-reduced model rats. To investigate the effects of oral intake of SC in humans, we performed a randomized, double-blind, placebo-controlled study. We found that cheek transepidermal water loss was significantly lower in the experimental group than in the control group at 4 weeks of ingestion. This study suggests that SC is effective and safe for the improvement of skin conditions.

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© 2013 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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