Changes in the Subarachnoid Space Precede Ventriculomegaly in Idiopathic Normal Pressure Hydrocephalus (iNPH)

Chifumi Iseki; Yoshimi Takahashi; Manabu Wada; Shigeki Arawaka; Toru Kawanami; Takeo Kato

doi:10.2169/internalmedicine.51.7254

CASE REPORTS

Changes in the Subarachnoid Space Precede Ventriculomegaly in Idiopathic Normal Pressure Hydrocephalus (iNPH)

Chifumi Iseki, Yoshimi Takahashi, Manabu Wada, Shigeki Arawaka, Toru Kawanami, Takeo Kato

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Keywords: idiopathic normal pressure hydrocephalus (iNPH), cerebrospinal fluid (CSF), magnetic resonance imaging (MRI), asymptomatic ventriculomegaly, subarachnoid space

JOURNAL OPEN ACCESS

2012 Volume 51 Issue 13 Pages 1751-1753

DOI https://doi.org/10.2169/internalmedicine.51.7254

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Abstract

We report on an 80-year-old woman who had shunt-responsive idiopathic normal pressure hydrocephalus (iNPH). Her brain MRI showed an initial change in the subarachnoid space (a disproportional narrowing of the subarachnoid space at the cerebral high convexities) at the age of 70 years, followed by enlargement of the ventricles (Evans index: 0.31) at the age of 78. The observation suggests that changes in the subarachnoid space may precede ventricular enlargement in iNPH.

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