Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
A Case of Disseminated Sporotrichosis Treated with Prednisolone, Immunosuppressants, and Tocilizumab under the Diagnosis of Rheumatoid Arthritis
Tetsuto YamaguchiSatoshi ItoYohei TakanoNaoto UmedaMizue GotoMasanobu HorikoshiTaichi HayashiDaisuke GotoIsao MatsumotoTakayuki Sumida
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JOURNAL OPEN ACCESS

2012 Volume 51 Issue 15 Pages 2035-2039

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Abstract

We encountered a disseminated sporotrichosis patient with polyarthritis and progressive skin ulcers, who had been previously treated with prednisolone, tocilizmab, tacrolims, and cyclophosphamide under the diagnosis of rheumatoid arthritis in another hospital. Making the diagnosis of leukocytoclasticvasculitis based on the clinical observation of skin ulcers, we intensified immunosuppressive therapy. Unfortunately, the patient developed septic shock. Blood culture revealed that the pathogenic organism was sporothrixschenckii. Any case of intractable arthritis or skin ulcers, which does not improve, despite adequate immunosuppressive therapy, is likely to be suspicious of sporotrichosis.

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© 2012 by The Japanese Society of Internal Medicine
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