Miliary Tuberculosis with Indeterminate Interferon Gamma Release Assay Results

Takahito Nei; Yousuke Fujisawa; Yuuki Izumi; Akito Tetsuka; Yosie Arita; Hiroshige Murata; Keisuke Sawai; Mitsunobu Kitamura; Hideki Miyachi; Yusuke Hosokawa; Koichi Akutsu; Takeshi Yamamoto; Keiji Tanaka; Akihiro Shinoyama

doi:10.2169/internalmedicine.52.0708

CASE REPORTS

Miliary Tuberculosis with Indeterminate Interferon Gamma Release Assay Results

Takahito Nei, Yousuke Fujisawa, Yuuki Izumi, Akito Tetsuka, Yosie Arita, Hiroshige Murata, Keisuke Sawai, Mitsunobu Kitamura, Hideki Miyachi, Yusuke Hosokawa, Koichi Akutsu, Takeshi Yamamoto, Keiji Tanaka, Akihiro Shinoyama

Author information

Takahito Nei
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Department of Infection Control and Prevention, Nippon Medical School, Main Hospital, Japan
Yousuke Fujisawa
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Yuuki Izumi
Department of Cardiovascular Medicine, Nippon Medical School, Japan
Akito Tetsuka
Department of Cardiovascular Medicine, Nippon Medical School, Japan
Yosie Arita
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Hiroshige Murata
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Keisuke Sawai
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Mitsunobu Kitamura
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Hideki Miyachi
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Yusuke Hosokawa
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Koichi Akutsu
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Takeshi Yamamoto
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Keiji Tanaka
Department of Intensive and Cardiovascular Care Unit, Nippon Medical School, Japan
Akihiro Shinoyama
Department of Infection Control and Prevention, Nippon Medical School, Main Hospital, Japan
Department of Clinical Laboratory, Nippon Medical School, Main Hospital, Japan

Keywords: miliary tuberculosis, hemophagocytosis, interferon gamma release assay (IGRA)

JOURNAL OPEN ACCESS

2013 Volume 52 Issue 22 Pages 2583-2585

DOI https://doi.org/10.2169/internalmedicine.52.0708

Details

Abstract

Recently, interferon gamma release assays (IGRAs) have become an important clinical tool for detecting latent tuberculosis. However, IGRA results may impede making a diagnosis. We herein present an interesting case of miliary tuberculosis with a nonspecific IGRA reaction due to hemophagocytosis.

Corresponding author

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