Follicular Thyroid Carcinoma Characterized by Abundant Stromal Components with Chondroid and Osseous Metaplasia in a Dog

Ryosuke KOBAYASHI; Naoaki YAMADA; Takashi KITAMORI; Fumiyo KITAMORI; Kazunari SATO; Takuya DOI; Yumi WAKO; Junko SATO; Minoru TSUCHITANI

doi:10.1292/jvms.13-0529

Pathology

Follicular Thyroid Carcinoma Characterized by Abundant Stromal Components with Chondroid and Osseous Metaplasia in a Dog

Ryosuke KOBAYASHI, Naoaki YAMADA, Takashi KITAMORI, Fumiyo KITAMORI, Kazunari SATO, Takuya DOI, Yumi WAKO, Junko SATO, Minoru TSUCHITANI

Author information

Ryosuke KOBAYASHI
Pathology Department, LSI Medience Corporation, 14–1 Sunayama, Kamisu-shi, Ibaraki 314–0255, Japan
Naoaki YAMADA
Pathology Department, LSI Medience Corporation, 14–1 Sunayama, Kamisu-shi, Ibaraki 314–0255, Japan
Takashi KITAMORI
Kitamori Animal Hospital, 2368 Kobayashi, Mobara-shi, Chiba 297–0074, Japan
Fumiyo KITAMORI
Kitamori Animal Hospital, 2368 Kobayashi, Mobara-shi, Chiba 297–0074, Japan
Kazunari SATO
Minamikoyasu Animal Hospital, 5–12–8 Minamikoyasu, Kimitsu-shi, Chiba 299–1162, Japan
Takuya DOI
Pathology Department, LSI Medience Corporation, 14–1 Sunayama, Kamisu-shi, Ibaraki 314–0255, Japan
Yumi WAKO
Pathology Department, LSI Medience Corporation, 14–1 Sunayama, Kamisu-shi, Ibaraki 314–0255, Japan
Junko SATO
Pathology Department, LSI Medience Corporation, 14–1 Sunayama, Kamisu-shi, Ibaraki 314–0255, Japan
Minoru TSUCHITANI
Pathology Department, LSI Medience Corporation, 14–1 Sunayama, Kamisu-shi, Ibaraki 314–0255, Japan

Keywords: canine, chondroid metaplasia, follicular thyroid carcinoma, osseous metaplasia, tumor stroma

JOURNAL FREE ACCESS

2014 Volume 76 Issue 8 Pages 1161-1164

DOI https://doi.org/10.1292/jvms.13-0529

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Abstract

A dog developed a cervical mass, and computed tomography verified a mass surrounding the trachea with some pulmonary masses. Histopathologically, the cervical mass was composed of malignant neoplastic cells showing follicular appearance which reacted positive for thyroglobulin on immunohistochemistry. A characteristic feature of the tumor was abundant and metaplastic stromal components. Anastomosed collagenous tissues connecting to capsule of the tumor were abundant in the stroma. In parts of the collagenous tissues, mature cartilages and bones were continuously formed. There was no cellular atypia or invasion in the components. We diagnosed this case as follicular thyroid carcinoma with metaplastic stroma. This is the first case report that characterizes stromal components with chondroid and osseous metaplasia in a canine thyroid carcinoma.

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