The fetus could not be considered a patient until ultrasonography stripped the fetus of his/her aura of mystery; until the origin and development of the fetus from embryo to neonate could be explained scientifically. Ultrasonographies enabled accurate delineation of normal and abnormal fetal anatomy with considerable detail and later on live moving pictures. Ultrasonographic imaging appears to have no harmful effect on the mother or on the fetus. The ability of prenatal ultrasonography to diagnose fetal abnormalities, both as a screening tool and for targeted examinations, has also been confirmed. The ability to perform invasive prenatal diagnostic procedures, such as amniocentesis, chorionic villus sampling, and cordocentesis as well as fetoscopy for fetal therapy has been significantly improved by real-time ultrasonography. Three-dimensional ultrasonography and MRI are now also available for fetal imaging. Recently, cell free fetal DNA released into maternal plasma is known as useful tool for non-invasive prenatal diagnosis of genetic diseases. The fetus may become our new patient in the near future.