Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Regular Papers
Safety Assessment of Rice Genetically Modified with Soybean Glycinin by Feeding Studies on Rats
Keiko MOMMAWataru HASHIMOTOHye-Jin YOONSachiko OZAWAYasuki FUKUDAShigeyuki KAWAIFumio TAKAIWAShigeru UTSUMIKousaku MURATA
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2000 Volume 64 Issue 9 Pages 1881-1886

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Abstract

  Feeding studies on rice genetically modified with soybean glycinin were performed on rats for four weeks. The rats were divided into three groups, each being fed on (I) only a commercial diet, (II) this diet plus control rice and (III) this diet plus rice genetically modified with glycinin. The rats were fed with 10 g/kg-weight of rice every day by oral administration. During the test period, the rats in every group grew well without marked differences in appearance, food intake, body weight, or cumulative body weight gain. There were also no significant differences in the blood count, blood composition or internal organ weights among the rats. Necropsy at the end of the experiment indicated neither pathological symptoms nor histopathological abnormalities in the liver and kidney. Judging from these results, the rice genetically modified with glycinin is considered to have been essentially the same in nutritional and biochemical characteristics as the control rice.

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© 2000 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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