Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science
Fused Heterocyclic Antioxidants: Antioxidative Activities of Hydrocoumarins in a Homogeneous Solution
Tomihiro NISHIYAMAJunichi OHNISHIYasuhiro HASHIGUCHI
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2001 年 65 巻 5 号 p. 1127-1133

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We compared the antioxidative activities of seven hydrocoumarins with those of α-tocopherol for the oxidation of tetralin and linoleic acid in a homogeneous solution. Hydrocoumarins exhibited a higher induction period than that of α-Toc in both systems. However, the rate of oxygen absorption during the induction period for α-Toc was slower than that of the hydrocoumarins in both systems. In addition, 6,7-dihydroxy-4,4-dimethylhydrocoumarin showed less cytotoxicity toward human fibroblasts than did 2,6-di-t-butyl-4-methylphenol.

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© 2001 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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