Inhibition of Osteoporosis Due to Restricted Food Intake by the Fish Oils DHA and EPA and Perilla Oil in the Rat

Liman SUN; Hajime TAMAKI; Tetsuji ISHIMARU; Tomokazu TERUYA; Yutaka OHTA; Naofumi KATSUYAMA; Isao CHINEN

doi:10.1271/bbb.68.2613

Food & Nutrition Science Notes

Inhibition of Osteoporosis Due to Restricted Food Intake by the Fish Oils DHA and EPA and Perilla Oil in the Rat

Liman SUN, Hajime TAMAKI, Tetsuji ISHIMARU, Tomokazu TERUYA, Yutaka OHTA, Naofumi KATSUYAMA, Isao CHINEN

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Keywords: osteoporosis, docosahesaenoic acid (DHA), eicosapentaenoic acid (EPA), deoxypyrisinolin, restricted food

JOURNAL FREE ACCESS

2004 Volume 68 Issue 12 Pages 2613-2615

DOI https://doi.org/10.1271/bbb.68.2613

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Abstract

Seven-week old female rats fed restricted foods including the fish oils Docosahesaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) and perilla oil with food intake decreased by 50%, had increases of fracture force and bone mineral density (BMD) and decreases in levels of Deoxypiridinoline (Dpd) and Calcium (Ca) in the urine, compared with those of rats with osteoporosis due to restricted soy bean oil food intake. Therefore, the fish oils DHA and EPA and perilla oil depressed excretion of urinary Ca and inhibited osteoporosis due to restricted food intake.

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