Effects of Fenugreek Seed Extract in Obese Mice Fed a High-Fat Diet

Toshiaki HANDA; Kohji YAMAGUCHI; Yoshikatsu SONO; Kazunaga YAZAWA

doi:10.1271/bbb.69.1186

Bioscience, Biotechnology, and Biochemistry

Online ISSN : 1347-6947
Print ISSN : 0916-8451

Food & Nutrition Science Notes

Effects of Fenugreek Seed Extract in Obese Mice Fed a High-Fat Diet

Toshiaki HANDA, Kohji YAMAGUCHI, Yoshikatsu SONO, Kazunaga YAZAWA

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Keywords: fenugreek, 4-hydroxyisoleucine, high-fat diet, triglyceride, obesity

JOURNAL FREE ACCESS

2005 Volume 69 Issue 6 Pages 1186-1188

DOI https://doi.org/10.1271/bbb.69.1186

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Abstract

It was found that fenugreek seed extract reduced the body weight gain induced by a high-fat diet in obese mice. The extract decreased plasma triglyceride gain induced by oil administration. The major component of the extract, 4-hydroxyisoleucine, also decreased plasma triglyceride gain. Consequently, fenugreek seed extract is expected to prevent the obesity induced by a high-fat diet.

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