Effect of Caffeine on the Body Fat and Lipid Metabolism of Rats Fed on a High-Fat Diet

Kazuo KOBAYASHI-HATTORI; Akie MOGI; Yoshinobu MATSUMOTO; Toshichika TAKITA

doi:10.1271/bbb.69.2219

Food & Nutrition Science Notes

Effect of Caffeine on the Body Fat and Lipid Metabolism of Rats Fed on a High-Fat Diet

Kazuo KOBAYASHI-HATTORI, Akie MOGI, Yoshinobu MATSUMOTO, Toshichika TAKITA

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Keywords: caffeine, body fat, lipid metabolism, catecholamine, obesity

JOURNAL FREE ACCESS

2005 Volume 69 Issue 11 Pages 2219-2223

DOI https://doi.org/10.1271/bbb.69.2219

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Abstract

The intake of caffeine (CF) at 0.025, 0.05 or 0.1% for 21 days progressively reduced the body fat mass and body fat percentage in Sprague-Dawley (SD) rats fed on a high-fat diet with increasing administration level. Moreover, CF increased the serum concentrations of catecholamines and free fatty acids in SD rats orally administered with CF (5 mg/kg). These results suggest that the intake of CF reduced body fat by lipolysis via catecholamines. CF has potential as a functional food ingredient with an anti-obesity action.

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