Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Food & Nutrition Science Notes
Effect of Vaccinium ashei reade Leaves on Angiotensin Converting Enzyme Activity in Vitro and on Systolic Blood Pressure of Spontaneously Hypertensive Rats in Vivo
Hiroshi SAKAIDAKoji NAGAOKouki HIGABungo SHIROUCHINao INOUEFumie HIDAKATakanori KAITeruyoshi YANAGITA
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2007 Volume 71 Issue 9 Pages 2335-2337

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Abstract

The hypotensive effects of Vaccinium ashei reade (blueberry) leaves were studied in vitro and in vivo. Blueberry leaf showed a strong inhibitory effect on angiotensin-converting enzyme activity in vitro. Additionally, feeding of blueberry leaf suppressed the development of essential hypertension in spontaneously hypertensive rats in vivo. These results promise the use of blueberry leaf as a source of dietary hypotensive components.

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© 2007 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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