Intra-Species Diversity between Seven Bifidobacterium adolescentis Strains Identified by Genome-Wide Tiling Array Analysis

Kazumasa YASUI; Mototsugu TABATA; Satoki YAMADA; Takashi ABE; Toshimichi IKEMURA; Ro OSAWA; Tohru SUZUKI

doi:10.1271/bbb.80843

Biochemistry & Molecular Biology Notes

Intra-Species Diversity between Seven Bifidobacterium adolescentis Strains Identified by Genome-Wide Tiling Array Analysis

Kazumasa YASUI, Mototsugu TABATA, Satoki YAMADA, Takashi ABE, Toshimichi IKEMURA, Ro OSAWA, Tohru SUZUKI

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Keywords: Bifidobacterium adolescentis, tiling array, genomic polymorphism, self-organizing map (SOM), DNA microarray

JOURNAL FREE ACCESS

2009 Volume 73 Issue 6 Pages 1422-1424

DOI https://doi.org/10.1271/bbb.80843

View "Advance Publication" version (June 7, 2009).

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Abstract

Six Bifidobacterium adolescentis strains, JCM1275, JCM1251, JCM7044, JCM7045, JCM7046, and 9-124, were analyzed using a tiling array designed according to the full genome sequence of ATCC15703. The results demonstrated deletion clusters along with single-gene mutations and deletions. Most deletions concerned genes involved in polysaccharide and cell-surface biogenesis. A dendrogram illustrating the deletions and mutations is presented and the evolution of B. adolescentis is discussed.

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