HorC, a Hop-Resistance Related Protein, Presumably Functions in Homodimer Form

Kazumaru IIJIMA; Koji SUZUKI; Shizuka ASANO; Tomoo OGATA; Yasushi KITAGAWA

doi:10.1271/bbb.90189

Microbiology & Fermentation Technology Notes

HorC, a Hop-Resistance Related Protein, Presumably Functions in Homodimer Form

Kazumaru IIJIMA, Koji SUZUKI, Shizuka ASANO, Tomoo OGATA, Yasushi KITAGAWA

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Keywords: horC, hop resistance, resistance-nodulation-cell division (RND) superfamily, half-size transporter, homodimer

JOURNAL FREE ACCESS

2009 Volume 73 Issue 8 Pages 1880-1882

DOI https://doi.org/10.1271/bbb.90189

View "Advance Publication" version (August 7, 2009).

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Abstract

To determine whether two HorC molecules coordinately form a single unit, the functional properties of covalently linked dimers of HorC encoded by tandemly fused horC genes were studied. Lactobacillus brevis introduced with the fused horC genes and a single horC gene exhibited same degree of resistance to hop compounds and cetyltrimethylammonium bromide. This suggests that HorC functions as a homodimer.

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