Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
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Phytoestrogens from Aspalathus linearis
Naomi ShimamuraToshio MiyaseKaoru UmeharaTsutomu WarashinaSatoshi Fujii
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2006 Volume 29 Issue 6 Pages 1271-1274

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Abstract

From the leaves of Aspalathus linearis, 24 known compounds and a new one, aspalalinin (25), were isolated. The structures of the compounds were determined mainly based on spectral evidence. The absolute configuration of aspalalinin was presented on the basis of X-ray analysis. Each isolate was assessed for its estrogenic activity by an estrogen ELISA assay. Compounds 12, 15, and 24 showed the estrogenic activity.

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© 2006 The Pharmaceutical Society of Japan
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