Predictive Factors of Major Adverse Cardiac Events in Acute Myocardial Infarction Patients Complicated by Cardiogenic Shock Undergoing Primary Percutaneous Coronary Intervention

Sang Yup Lim; Myung Ho Jeong; Eun Hui Bae; Weon Kim; Ju Han Kim; Young Joon Hong; Hyung Wook Park; Dong Goo Kang; Yeon Sang Lee; Kye Hun Kim; Sang Hyun Lee; Kyung Ho Yun; Seo Na Hong; Jeong Gwan Cho; Young Keun Ahn; Jong Chun Park; Byoung Hee Ahn; Sang Hyung Kim; Jung Chaee Kang

doi:10.1253/circj.69.154

Clinical Investigation

Predictive Factors of Major Adverse Cardiac Events in Acute Myocardial Infarction Patients Complicated by Cardiogenic Shock Undergoing Primary Percutaneous Coronary Intervention

Sang Yup Lim, Myung Ho Jeong, Eun Hui Bae, Weon Kim, Ju Han Kim, Young Joon Hong, Hyung Wook Park, Dong Goo Kang, Yeon Sang Lee, Kye Hun Kim, Sang Hyun Lee, Kyung Ho Yun, Seo Na Hong, Jeong Gwan Cho, Young Keun Ahn, Jong Chun Park, Byoung Hee Ahn, Sang Hyung Kim, Jung Chaee Kang

Author information

Sang Yup Lim
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Myung Ho Jeong
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Eun Hui Bae
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Weon Kim
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Ju Han Kim
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Young Joon Hong
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Hyung Wook Park
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Dong Goo Kang
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Yeon Sang Lee
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Kye Hun Kim
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Sang Hyun Lee
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Kyung Ho Yun
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Seo Na Hong
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Jeong Gwan Cho
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Young Keun Ahn
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Jong Chun Park
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Byoung Hee Ahn
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Sang Hyung Kim
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences
Jung Chaee Kang
The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences

Keywords: Coronary diseases, Myocardial infarction, Prognosis, Shock

JOURNAL FREE ACCESS

2005 Volume 69 Issue 2 Pages 154-158

DOI https://doi.org/10.1253/circj.69.154

Details

Abstract

Background The aim of this study was to assess in-hospital mortality and major adverse cardiac events (MACE) during long-term clinical follow-up of patients who developed cardiogenic shock (CS) after acute myocardial infarction (AMI) and who underwent primary percutaneous coronary intervention (PCI). Methods and Results The data from 147 patients with CS after AMI (61.7 ±10.4 years, M:F =156:99) who underwent primary PCI at Chonnam National University Hospital between January 1999 and December 2002 were analyzed: clinical characteristics, coronary angiographic findings and mortality during admission, and MACE during a 1-year clinical follow-up. Of the enrolled patients, 121 patients survived (group I, M:F =94:27) and 26 died (group II, M:F =14:12) during admission. By binary logistic regression analysis, in-hospital death was associated with low Thrombolysis In Myocardial Infarction (TIMI) flow after coronary revascularization (p=0.02, odds ratio (OR) =1.3). Eighty-nine patients (60.5%) survived without MACE during the 1-year clinical follow-up and MACE was associated with a C-reactive protein (CRP) of more than 1 mg/dl (p=0.002, OR =6.3) and low TIMI flow after coronary revascularization (p<0.001, OR =7.8). Conclusions Primary PCI achieving TIMI 3 flow reduces in-hospital death in AMI with CS. High concentration of CRP and low TIMI flow are associated with MACE during long-term clinical follow-up. (Circ J 2005; 69: 154 - 158)

Corresponding author

Register with J-STAGE for free!