Accuracy of Nonstenotic Coronary Atherosclerosis Assessment by Multi-Detector Computed Tomography

Tetsuya Hara; Shinichiro Yamada; Takatoshi Hayashi; Yoshihiro Ikeda; Kohei Yamashiro; Kazuo Mizutani; Sachiyo Iwata; Katsunori Okajima; Yasue Tsukishiro; Kensuke Matsumoto; Takafumi Akagami; Hiroyuki Kumagai; Mitsuo Kinugasa; Michihiko Inoue; Naoki Murai; Ichiro Izawa; Teishi Kajiya

doi:10.1253/circj.71.911

Clinical Investigation

Accuracy of Nonstenotic Coronary Atherosclerosis Assessment by Multi-Detector Computed Tomography

Tetsuya Hara, Shinichiro Yamada, Takatoshi Hayashi, Yoshihiro Ikeda, Kohei Yamashiro, Kazuo Mizutani, Sachiyo Iwata, Katsunori Okajima, Yasue Tsukishiro, Kensuke Matsumoto, Takafumi Akagami, Hiroyuki Kumagai, Mitsuo Kinugasa, Michihiko Inoue, Naoki Murai, Ichiro Izawa, Teishi Kajiya

Author information

Tetsuya Hara
Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School
Shinichiro Yamada
Department of Cardiology, Himeji Cardiovascular Center
Takatoshi Hayashi
Department of Cardiology, Himeji Cardiovascular Center
Yoshihiro Ikeda
Department of Cardiology, Himeji Cardiovascular Center
Kohei Yamashiro
Department of Cardiology, Himeji Cardiovascular Center
Kazuo Mizutani
Department of Cardiology, Himeji Cardiovascular Center
Sachiyo Iwata
Department of Cardiology, Himeji Cardiovascular Center
Katsunori Okajima
Department of Cardiology, Himeji Cardiovascular Center
Yasue Tsukishiro
Department of Cardiology, Himeji Cardiovascular Center
Kensuke Matsumoto
Department of Cardiology, Himeji Cardiovascular Center
Takafumi Akagami
Department of Cardiology, Himeji Cardiovascular Center
Hiroyuki Kumagai
Department of Cardiology, Himeji Cardiovascular Center
Mitsuo Kinugasa
Department of Cardiology, Himeji Cardiovascular Center
Michihiko Inoue
Department of Cardiology, Himeji Cardiovascular Center
Naoki Murai
Department of Cardiology, Himeji Cardiovascular Center
Ichiro Izawa
Department of Radiological Technology, Himeji Cardiovascular Center
Teishi Kajiya
Department of Cardiology, Himeji Cardiovascular Center

Keywords: Coronary plaque, IVUS, MDCT, Proximal lesion

JOURNAL FREE ACCESS

2007 Volume 71 Issue 6 Pages 911-914

DOI https://doi.org/10.1253/circj.71.911

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Abstract

Background The ability to evaluate coronary stenosis using multi-detector computed tomography (MDCT) has been well discussed. In contrast, several studies demonstrated that the plaque burden measured by intravascular ultrasound (IVUS) has a relationship to the risk of cardiovascular events. the accuracy of MDCT was studied to determine plaque and vessel size compared with IVUS. Methods and Results Fifty-six proximal lesions (American College of Cardiology/American Heart Association classification: segment 1, 5, 6) from 33 patients were assessed using MDCT and IVUS. The plaque and vessel area were measured from the cross-sectional image using both MDCT and IVUS. Eight coronary artery lesions with motion artifacts and heavily calcified plaques were excluded from the analysis. The vessel and lumen size evaluated using MDCT were closely correlated with those evaluated by IVUS (R²=0.614, 0.750 respectively). Furthermore, there was a strong correlation between percentage plaque area assessed by MDCT and IVUS (R²=0.824). Conclusion MDCT can noninvasively quantify coronary atherosclerotic plaque with good correlation compared with IVUS in patients with atherosclerosis. (Circ J 2007; 71: 911 - 914)

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