2003 Volume 51 Issue 9 Pages 1089-1091
Two new pregnane glycosides (1, 2) together with two known saponins were isolated from the rhizomes of Dioscorea futschauensis R. KUNTH. The structures of 1 and 2 were established as 16α-methoxyl-3β-[(O-α-L-rhamnopyranosyl-(1→2)-O-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranosyl)oxy]pregn-5-en-20-one and 21-methoxyl-3β-[(O-α-L-rhamnopyranosyl-(1→2)-O-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranosyl)oxy]pregn-5,16-en-20-one, respectively, on the basis of two-dimension NMR (2D NMR) and other spectral analysis. Their in vitro bioactivity against plant pathogenic fungus Pyricularia oryzae and osteoblastic proliferation stimulatory activity in the UMR106 cell line were evaluated.
