Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Cordycedipeptide A, a New Cyclodipeptide from the Culture Liquid of Cordyceps sinensis (BERK.) SACC.
Jing-Ming JiaXiao-Chi MaChun-Fu WuLi-Jun WuGao-sheng Hu
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2005 Volume 53 Issue 5 Pages 582-583

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Abstract

A new cyclodipeptide named as cordycedipeptide A, a new natural compound and two known compound were isolated from the culture liquid of Cordyceps sinensis (BERK.) SACC. Their structures were elucidated as 3-acetamino-6-isobutyl-2,5-dioxopiperazine (1), 3-isopropyl-6-isobutyl-2,5-dioxopiperazine (2) and 3,6-di(4-hydroxy)benzyl-2,5-dioxopiperazine (3) by 1D and 2D-NMR techniques. The cytotoxic assay showed compound 1 had the cytotoxic activities to L-929, A375, and Hela.

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© 2005 The Pharmaceutical Society of Japan
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