Chemical Constituents from Seeds of Panax ginseng: Structure of New Dammarane-Type Triterpene Ketone, Panaxadione, and HPLC Comparisons of Seeds and Flesh

Sachiko Sugimoto; Seikou Nakamura; Hisashi Matsuda; Niichiro Kitagawa; Masayuki Yoshikawa

doi:10.1248/cpb.57.283

Notes

Chemical Constituents from Seeds of Panax ginseng: Structure of New Dammarane-Type Triterpene Ketone, Panaxadione, and HPLC Comparisons of Seeds and Flesh

Sachiko Sugimoto, Seikou Nakamura, Hisashi Matsuda, Niichiro Kitagawa, Masayuki Yoshikawa

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Keywords: panaxadione, Panax ginseng, dammarane-type triterpene, ginseng seed, Araliaceae

JOURNAL FREE ACCESS

2009 Volume 57 Issue 3 Pages 283-287

DOI https://doi.org/10.1248/cpb.57.283

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Abstract

A new dammarane-type triterpene ketone, panaxadione, was isolated from the seeds of Panax ginseng C. A. MEYER (Araliaceae) together with two dammarane-type and lupane-type triterpenes, an aromatic oligoglycoside, three sterol glycosides, and three dammarane-type triterpene oligoglycosides (ginsenosides Rd, Re, and Rg₂). The structure of a new compound was elucidated on the basis of physicochemical evidence. The relative contents of major ginsenosides in the seeds were compared with those of the flesh parts of young and mature fruits.

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