Three New Stereoisomers of Condensed Tannins from the Roots of Rosa multiflora

Kwan Hee Park; Sung Kyu Kim; Sun Eun Choi; Joo Hee Kwon; Myung Hwan Oh; Min Won Lee

doi:10.1248/cpb.58.1227

Notes

Three New Stereoisomers of Condensed Tannins from the Roots of Rosa multiflora

Kwan Hee Park, Sung Kyu Kim, Sun Eun Choi, Joo Hee Kwon, Myung Hwan Oh, Min Won Lee

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Keywords: Rosa multiflora, condensed tannin, proguibourtinidin, profisetinidin, phlobatannin

JOURNAL FREE ACCESS

2010 Volume 58 Issue 9 Pages 1227-1231

DOI https://doi.org/10.1248/cpb.58.1227

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Abstract

Three new stereoisomers of condensed tannins (1—3), and four known phenolic compounds (4—7) were isolated from the 80% acetone extract of the roots of Rosa multiflora Thunberg. The structures of these compounds were elucidated using 1D/2D NMR, high resolution (HR)-MS, and circular dichroism (CD) spectra. In order to evaluate their anti-oxidative and anti-inflammatory activities, their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and inhibitory activity on nitric oxide (NO) production were determined.

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