Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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New Prenylated C6–C3 Compounds from the Twigs of Illicium anisatum
Miwa KuboNaoki ShimaKenichi HaradaHideaki HiokiYoshiyasu Fukuyama
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2011 Volume 59 Issue 7 Pages 898-901

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Abstract

Two new prenylated C6–C3 compounds, cycloillicinone (1) and 4-allyl-2-methoxy-6-(2-methylbut-3-en-2-yl)phenol (2), were isolated from the twigs of Illicium anisatum, and their structures were determined by 2D-NMR methods. Cycloillicinone (1) is a unique prenylated C6–C3 that is appended with an additional geranyl unit. Compound 2 was found to show moderate neurite-outgrowth promoting activity in primary cultured rat cortical neurons at a concentration of 10 μM.

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© 2011 The Pharmaceutical Society of Japan
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