Clinical Pediatric Endocrinology
Online ISSN : 1347-7358
Print ISSN : 0918-5739
ISSN-L : 0918-5739
Original Article
A Case of Primary Hyperparathyroidism in Childhood Found by a Chance Hematuria
Yasuhisa Ohata, Takehisa Yamamoto, Yukihiro Kitai, Yoshimi Mizoguchi, Masaru Iwaki, Kiyoaki Sumi, Yasuhiro Fujikawa, Minoru Koga, Hideki Sugao, Tsunesuke Shimotsuji, Keiichi Ozono
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Keywords: hyperparathyroidism, hematuria, calcium, phosphate, bone mineral density
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2007 Volume 16 Issue 1 Pages 11-16

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Abstract

A 10-yr-old boy visited Minoh City Hospital complaining of gross hematuria. Laboratory investigations revealed hypercalcemia, hypophosphatemia, and elevated serum levels of parathyroid hormone. A stone was found in the right ureter with drip infusion pyelography. A parathyroid adenoma was successfully diagnosed with computed tomography, ultrasonography, and methoxy-2-isobutyl isonitrile (MIBI) scintigraphy. Multiple endocrine neoplasia was ruled out by normal results of endocrine laboratory examinations. Extracorporeal shock wave lithotripsy was performed to treat the urolithiasis, and the parathyroid adenoma was surgically removed. Primary hyperparathyroidism is rare in childhood; however, this case suggests that gross hematuria is an important sign of hyperparathyroidism.

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© 2007 by The Japanese Society for Pediatric Endocrinology
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