We report first results about the ability of low density amorphous ice nanolayers to behave as a “matrix” and trap monomeric neutral glycine molecules at 125 K, a temperature much greater than the commonly used liquid He temperature region. FTIR-RAS spectra of those monomeric neutral glycine molecules adsorbed on low dense amorphous ice were obtained for the first time and indicate that glycine adsorbs molecularly with the carboxylic group and the nitrogen atom hydrogen-bonded to the ice surface. [DOI: 10.1380/ejssnt.2009.693]