Novel design of large-mode-area leakage channel fibers (LCFs) with a single air-hole ring surrounding a multi-unit-cell solid core is investigated for realizing robust single-mode and low bending loss characteristics. We perform detailed numerical simulations using a finite element method, and we show that the proposed LCFs with a solid core formed by multiple missing neighboring air-holes can achieve much lower bending losses compared with the reported LCF with six large air-holes.