Global Fibrinolytic Capacity in Patients with Subclinical Hypothyroidism

Sibel GULDIKEN; Muzaffer DEMIR; Burhan TURGUT; Betul Ugur ALTUN; Ender ARIKAN; Mujdat KARA

doi:10.1507/endocrj.52.363

NOTES

Global Fibrinolytic Capacity in Patients with Subclinical Hypothyroidism

Sibel GULDIKEN, Muzaffer DEMIR, Burhan TURGUT, Betul Ugur ALTUN, Ender ARIKAN, Mujdat KARA

Author information

Keywords: Subclinical hypothyroidism, Global fibrinolytic capacity, Hypothyroidism, Fibrinolytic system

JOURNAL FREE ACCESS

2005 Volume 52 Issue 3 Pages 363-367

DOI https://doi.org/10.1507/endocrj.52.363

Details

Abstract

Subclinical hypothyroidism (SH) represents the earliest stages of hypothyroidism but the benefits of detecting and treating SH are not well known. The aim of this study was to evaluate the alterations in global fibrinolytic capacity (GFC), which indicates the overall fibrinolytic activity, in patients with SH. The study group comprised of 15 patients with SH and 15 healthy controls. The GFC was significantly lower in patients with SH than in control group (p<0.002). This result suggests a relative hypercoagulable state in SH.

Corresponding author

Register with J-STAGE for free!