Multiple Bone Fractures Found in a Young Sarcoidosis Patient with Long Stable Disease

Tomohiro HANDA; Sonoko NAGAI; Isao ITO; Michio SHIGEMATSU; Kunio HAMADA; Masanori KITAICHI; Kosuke OHTA; Takateru IZUMI; Michiaki MISHIMA

doi:10.2169/internalmedicine.44.1269

CASE REPORTS

Multiple Bone Fractures Found in a Young Sarcoidosis Patient with Long Stable Disease

Tomohiro HANDA, Sonoko NAGAI, Isao ITO, Michio SHIGEMATSU, Kunio HAMADA, Masanori KITAICHI, Kosuke OHTA, Takateru IZUMI, Michiaki MISHIMA

Author information

Tomohiro HANDA
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
Sonoko NAGAI
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
Isao ITO
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University
Michio SHIGEMATSU
Department of Internal Medicine, Chitose City Hospital, Hokkaido
Kunio HAMADA
Department of Respiratory Medicine, Sumitomo Hospital, Osaka
Masanori KITAICHI
Department of Laboratory Medicine and Pathology National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka
Kosuke OHTA
Kyoto Central Clinic
Takateru IZUMI
Kyoto Central Clinic
Michiaki MISHIMA
Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University

Keywords: osseous sarcoidosis, bone fracture, multiple organ involvement

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 12 Pages 1269-1275

DOI https://doi.org/10.2169/internalmedicine.44.1269

Details

Abstract

A 22-year-old Japanese man was found to have bilateral hilar lymphadenopathy (BHL), and was diagnosed with sarcoidosis in 1995. He was followed without treatment until 2002, when a bone fracture due to osseous sarcoidosis was found in his left thumb. Despite systemic treatment with corticosteroid and methotrexate, a new bone lesion developed in his right foot and his right middle finger was fractured. The patient also suffered multiple organ involvements including brain and muscle lesions. This is the first report of a sarcoidosis patient who presented with BHL, and developed bone fractures after a long stable period of more than 5 years.

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