Fulminant Massive Gas Gangrene Caused by Clostridium perfringens

Shoji KURODA; Yumi OKADA; Masaki MITA; Yasuo OKAMOTO; Hirotaka KATO; Shigemitsu UEYAMA; Ikuzo FUJII; Sumiharu MORITA; Yasuaki YOSHIDA

doi:10.2169/internalmedicine.44.499

CASE REPORTS

Fulminant Massive Gas Gangrene Caused by Clostridium perfringens

Shoji KURODA, Yumi OKADA, Masaki MITA, Yasuo OKAMOTO, Hirotaka KATO, Shigemitsu UEYAMA, Ikuzo FUJII, Sumiharu MORITA, Yasuaki YOSHIDA

Author information

Shoji KURODA
Department of Internal Medicine, Miki Sanyo Hospital
Yumi OKADA
Department of Internal Medicine, Miki Sanyo Hospital
Masaki MITA
Department of Internal Medicine, Miki Sanyo Hospital
Yasuo OKAMOTO
Department of Internal Medicine, Miki Sanyo Hospital
Hirotaka KATO
Department of Internal Medicine, Miki Sanyo Hospital
Shigemitsu UEYAMA
Department of Internal Medicine, Miki Sanyo Hospital
Ikuzo FUJII
Department of Internal Medicine, Miki Sanyo Hospital
Sumiharu MORITA
Department of Internal Medicine, Miki Sanyo Hospital
Yasuaki YOSHIDA
Department of Internal Medicine, Miki Sanyo Hospital

Keywords: gas gangrene, Clostridium perfringens, anti-Clostridium perfringens enterotoxinA polyclonal antibody

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 5 Pages 499-502

DOI https://doi.org/10.2169/internalmedicine.44.499

Details

Abstract

Clostridium perfringens (C.P) gas gangrene is one of the most fulminant infectious diseases. We encountered fulminant massive gas gangrene in a 56- year-old man with alcoholic liver cirrhosis. The patient died 14 hours after diagnosis of gas gangrene (54 hours after admission). Dramatic changes in abdominal CT imaging revealed development of a massive volume of gas in the intra-portal vein, retroperitoneum and abdominal subcutaneous tissue within 24 hours. We also proved C.P infection by immunohistological staining, leading to a diagnosis of C.P gas gangrene.

Corresponding author

Register with J-STAGE for free!