Disseminated Cryptococcosis Complicated with Bilateral Pleural Effusion and Ascites during Corticosteroid Therapy for Organizing Pneumonia with Myelodysplastic Syndrome

Hiroyuki Kamiya; Rie Ishikawa; Atsuko Moriya; Aiko Arai; Kozo Morimoto; Tsunehiro Ando; Soichiro Ikushima; Masaru Oritsu; Tamiko Takemura

doi:10.2169/internalmedicine.47.0898

CASE REPORTS

Disseminated Cryptococcosis Complicated with Bilateral Pleural Effusion and Ascites during Corticosteroid Therapy for Organizing Pneumonia with Myelodysplastic Syndrome

Hiroyuki Kamiya, Rie Ishikawa, Atsuko Moriya, Aiko Arai, Kozo Morimoto, Tsunehiro Ando, Soichiro Ikushima, Masaru Oritsu, Tamiko Takemura

Author information

Keywords: disseminated cryptococcosis, pleural effusion, ascites, serositis, cryptococcal antigen

JOURNAL OPEN ACCESS

2008 Volume 47 Issue 22 Pages 1981-1986

DOI https://doi.org/10.2169/internalmedicine.47.0898

Details

Abstract

An 83-year-old man with myelodysplastic syndrome was admitted to our hospital due to dyspnea and abnormal shadows on chest X-ray films during corticosteroid therapy for organizing pneumonia. He was diagnosed as having disseminated cryptococcosis with pulmonary lesions after detecting Cryptococcus neoformans. Both bilateral pleural effusion with or without ipsilateral pulmonary lesions and ascites ensued, and it was assumed that both direct involvement and serositis were associated with the fluid accumulation. Cryptococcal yeast was only detected in the right pleural effusion, and the titer of cryptococcal antigen was quite different between body cavities, even though it was positive in all sites.

Corresponding author

Register with J-STAGE for free!