A Case of Takayasu's Arteritis Associated with Human Leukocyte Antigen A24 and B52 Following Resolution of Ulcerative Colitis and Subacute Thyroiditis

Yoshiro Horai; Tomoya Miyamura; Karin Shimada; Soichiro Takahama; Rumi Minami; Masahiro Yamamoto; Eiichi Suematsu

doi:10.2169/internalmedicine.50.4385

CASE REPORTS

A Case of Takayasu's Arteritis Associated with Human Leukocyte Antigen A24 and B52 Following Resolution of Ulcerative Colitis and Subacute Thyroiditis

Yoshiro Horai, Tomoya Miyamura, Karin Shimada, Soichiro Takahama, Rumi Minami, Masahiro Yamamoto, Eiichi Suematsu

Author information

Yoshiro Horai
Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization Kyushu Medical Center, Japan
Tomoya Miyamura
Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization Kyushu Medical Center, Japan
Karin Shimada
Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization Kyushu Medical Center, Japan
Soichiro Takahama
Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization Kyushu Medical Center, Japan
Rumi Minami
Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization Kyushu Medical Center, Japan
Masahiro Yamamoto
Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization Kyushu Medical Center, Japan
Eiichi Suematsu
Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization Kyushu Medical Center, Japan

Keywords: Takayasu's arteritis, ulcerative colitis, subacute thyroiditis, human leukocyte antigen

JOURNAL OPEN ACCESS

2011 Volume 50 Issue 2 Pages 151-154

DOI https://doi.org/10.2169/internalmedicine.50.4385

Details

Abstract

A 46-year-old female with a past history of ulcerative colitis (UC) was diagnosed with subacute thyroiditis (SAT), which improved with prednisolone (PSL) treatment (60 mg/day). The dose of PSL was gradually decreased, however upper back and neck pain and chest discomfort developed. The patient was diagnosed with Takayasu's arteritis (TA) based on wall thickening and luminal narrowing of the left common carotid artery and the left subclavian artery. The result of human leukocyte antigen typing analysis was A24 and B52 positive. These findings suggested that common genetic factors may be important for the etiology of TA, UC and SAT. This is the first report of TA that developed following UC and SAT.

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