Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Weber-Christian Disease Developing into Mediastinitis and Pleuritis with Massive Pleural Effusion
Shoji HirasakiKazutoshi MurakamiTatsuya KanamoriTakaaki MizushimaYoshihisa HanayamaNorio Koide
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JOURNAL OPEN ACCESS

2012 Volume 51 Issue 8 Pages 943-947

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Abstract

A 53-year-old man visited our hospital complaining of high fever. Chest computed tomography showed left pleural effusion and mediastinitis. He developed painful red subcutaneous nodules in his bilateral lower extremities. Thoracoscopy-assisted exploratory excision showed visceral pleura thickening; panniculitis in the periaortic area was histologically proven. The patient was treated with corticosteroid therapy which immediately reduced the fever. Subsequent imaging examinations after corticosteroid therapy showed improvement of mediastinitis and pleural effusion. This case reminds us that Weber-Christian disease (WCD) should be included in the differential diagnosis of mediastinitis although WCD is rarely associated with thoracic involvement.

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© 2012 by The Japanese Society of Internal Medicine
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