Brugada-like Electrocardiographic Pattern Unmasked by Fever

Rie Wakita; Ichiro Watanabe; Yasuo Okumura; Takeshi Yamada; Yasuhiro Takagi; Tatsuya Kofune; Kimie Okubo; Riko Masaki; Hidezou Sugimura; Naohiro Oshikawa; Satoshi Saito; Yukio Ozawa; Katsuo Kanmatsuse

doi:10.1536/jhj.45.163

Case Reports

Brugada-like Electrocardiographic Pattern Unmasked by Fever

Rie Wakita, Ichiro Watanabe, Yasuo Okumura, Takeshi Yamada, Yasuhiro Takagi, Tatsuya Kofune, Kimie Okubo, Riko Masaki, Hidezou Sugimura, Naohiro Oshikawa, Satoshi Saito, Yukio Ozawa, Katsuo Kanmatsuse

Author information

Rie Wakita
Second Department of Medicine, Nihon University School of Medicine
Ichiro Watanabe
Second Department of Medicine, Nihon University School of Medicine
Yasuo Okumura
Second Department of Medicine, Nihon University School of Medicine
Takeshi Yamada
Second Department of Medicine, Nihon University School of Medicine
Yasuhiro Takagi
Second Department of Medicine, Nihon University School of Medicine
Tatsuya Kofune
Second Department of Medicine, Nihon University School of Medicine
Kimie Okubo
Second Department of Medicine, Nihon University School of Medicine
Riko Masaki
Second Department of Medicine, Nihon University School of Medicine
Hidezou Sugimura
Second Department of Medicine, Nihon University School of Medicine
Naohiro Oshikawa
Second Department of Medicine, Nihon University School of Medicine
Satoshi Saito
Second Department of Medicine, Nihon University School of Medicine
Yukio Ozawa
Second Department of Medicine, Nihon University School of Medicine
Katsuo Kanmatsuse
Second Department of Medicine, Nihon University School of Medicine

Keywords: Brugada syndrome Fever, Pilsicainide, Ventricular premature beat, Electrocardiogram

JOURNAL FREE ACCESS

2004 Volume 45 Issue 1 Pages 163-167

DOI https://doi.org/10.1536/jhj.45.163

Details

Abstract

Brugada syndrome is characterized by right bundle branch block morphology and ST-segment elevation in the right precordial leads and a propensity to develop ventricular arrhythmias. Mutations in a cardiac sodium channel gene have been linked to this syndrome, and the ionic mechanisms responsible for the electrocardiographic phenotype are temperature-dependent. This case report describes a patient in whom a typical Brugada ECG pattern developed during fever and could be reproduced at normal body temperature by administration of pilsicainide.

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