An experimental-numerical hybrid method for analyzing stresses in a local region is proposed in this paper. Strains along the boundary of the local analysis region are measured using strain gauges. The tractions along the boundary are obtained from the measured strains and they are used as the boundary condition for the local model. Then, the stress distributions within the local region can be obtained by finite element analysis. The proposed method is applied to the stress analysis of a bicycle frame. By measuring strains of the bicycle frame using multiple three-element rosette strain gauges, the boundary condition for a local finite element model is obtained. Then, the stress distributions are obtained by finite element direct analysis using the measured boundary condition. It can be considered that the reliable results are obtained by the proposed method because the measured values are used as the boundary condition.