Anti-fouling paints for ship bottoms, that are no harm to the environment, are desired in the situations, such as prohibition of global use of a tributyltin compound (TBT), the sudden rise in crude oil price, and the reduction of the amount of carbon dioxide discharge. TBT not only causes usual environmental pollution, but also includes the danger of causing endocrine disrupters. Therefore, an anti-fouling paint, must not contain an elution element. Under these circumstances, new anti-fouling systems, i) a patient that does not contain an elution element into the seawater at all, and ii) a biofilm. Moreover, from a viewpoint of energy saving, we aim at developing (iii) paints of energy saving further from the self-polish type paint that has the high energy-saving effect. By making paint film realize the function of the living thing gained in process of evolution, we are developing paint films of unprecedented low frictional resistance. Here, I introduce about the new anti-fouling system by which we are advancing the stare examination of anti-fouling paint for the future.