New multicomponent V-based glassy alloy powder has been synthesized by mechanical alloying a mixture of elemental V₄₅Zr₂₀Ni₂₀Cu₁₀Al_2.5Pd_2.5 powder at room temperature, using a low energy ball mill. The glassy powder of the end-product (720 ks) in which its glass transition temperature (T_g) lies at a rather high temperature (745 K), crystallizes through two sharp exothermic reactions at 843 K and 919 K, respectively. The total enthalpy change of crystallization (ΔH_x) is −1.78 kJ/mol. The supercooled liquid region before crystallization, ΔT_x of the synthesized glassy powder shows a high value (98 K) for a metallic glassy system. The reduced glass transition temperature (ratio between T_g and liquidus temperatures, T_l (T_g⁄T_l)) was found to be 0.52.