Bone Loss and Reduced Bone Quality of the Human Femur after Total Hip Arthroplasty under Stress-Shielding Effects by Titanium-Based Implant

Yoshihiro Noyama; Takuya Miura; Takuya Ishimoto; Takahiro Itaya; Mitsuo Niinomi; Takayoshi Nakano

doi:10.2320/matertrans.M2011358

Yoshihiro Noyama, Takuya Miura, Takuya Ishimoto, Takahiro Itaya, Mitsuo Niinomi, Takayoshi Nakano

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Keywords: titanium, biomaterial, total hip arthroplasty, stress-shielding effect, biological apatite (BAp), preferential orientation, bone quality, finite element analysis (FEA)

JOURNAL FREE ACCESS

2012 Volume 53 Issue 3 Pages 565-570

DOI https://doi.org/10.2320/matertrans.M2011358

View "Advance Publication" version (February 15, 2012).

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Abstract

The present work was aimed at clarifying the stress-shielding effect caused by hip-joint implantation into a femur by using a human cadaver with a cementless hip implant. In particular, bone quality was assessed from the standpoint of preferential c-axis orientation of biological apatite (BAp). Comparing the implanted side to the non-implanted side, a finite element analysis (FEA) indicated that artificial hip-joint implantation had a significant stress-shielding effect on the femur. The results also showed a marked decrease in the degree of preferential BAp orientation as well as bone loss in the medial-proximal femur. This is the first report showing a reduction in the degree of preferential BAp orientation due to a stress-shielding effect after artificial hip-joint implantation. Since preferential BAp orientation is an important index for determining bone mechanical function, these findings should be taken into account in future artificial hip-joint designs, especially those involving the stem component.

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