De Novo Cerebral Aneurysms Manifesting as Repeated Subarachnoid Hemorrhage and Cerebral Ischemic Stroke —Case Report—

Hirokatsu OSAWA; Kazuhiro FUKUI; Goro OTSUKA; Ken-ichi HATTORI; Tatsunari SATAKE; Motoko MIYAZAKI

doi:10.2176/nmc.42.391

Case Reports

De Novo Cerebral Aneurysms Manifesting as Repeated Subarachnoid Hemorrhage and Cerebral Ischemic Stroke

—Case Report—

Hirokatsu OSAWA, Kazuhiro FUKUI, Goro OTSUKA, Ken-ichi HATTORI, Tatsunari SATAKE, Motoko MIYAZAKI

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Keywords: de novo aneurysm, subarachnoid hemorrhage, cerebral ischemic stroke, hypertrophy of intima, neuroradiological follow up

JOURNAL OPEN ACCESS

2002 Volume 42 Issue 9 Pages 391-395

DOI https://doi.org/10.2176/nmc.42.391

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Abstract

A 29-year-old man suffered repeated subarachnoid hemorrhage and cerebral ischemic stroke over a period of 6 years. Cerebral angiography at each episode disclosed development of multiple de novo aneurysms at the bilateral middle cerebral arteries (MCAs), internal carotid arteries, right anterior cerebral artery, and right vertebral artery. Two of the ruptured aneurysms were treated by surgical and endovascular treatment, but he died of the effects of rupture of a de novo right MCA aneurysm. Histological examination at autopsy disclosed marked degenerative changes in all layers of the cerebral vessels, which were probably congenital in origin.

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