The corrugated steel web PC box bridge is one of many types of hybrid steel and concrete structure that have recently been developed. However, this type of bridge has not yet been adopted for railway bridges in Japan. In this paper, we investigate the fatigue durability of joints connecting a corrugated steel web plate with a concrete slab. As a result, it was verified that two different joints, the constraint reinforced bar type and the tie plate type, have sufficiently high fatigue durability.