The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
ANTIMETABOLITES PRODUCED BY MICROORGANISMS. X
L-2-AMINO-4-(2-AMINOETHOXY)-TRANS-3-BUTENOIC ACID
DAVID L. PRUESSJAMES P. SCANNELLMARTHA KELLETTHELEN A. AXJEAN JANECEKTHOMAS H. WILLIAMSARTHUR STEMPELJULIUS BERGER
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1974 Volume 27 Issue 4 Pages 229-233

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Abstract

L-2-Amino-4-(2-aminoethoxy)-trans-3-butenoic acid was isolated from a fermentation broth of an unidentified species of Streptomyces, X-11, 085. This substance inhibited the growth of Streptomyces cellulosae in a chemically defined minimal medium. The growth inhibition was reversed noncompetitively by L-cysteine and competitively by L-lysine, L-arginine and L-ornithine.

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© Japan Antibiotics Research Association
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