The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
SF2487, A NEW POLYETHER ANTIBIOTIC PRODUCED BY ACTINOMADURA
MASAHIRO HATSU, TORU SASAKI, SHINJI MIYADOH, HIRO-OMI WATABE, YASUO TAKEUCHI, YOSHIO KODAMA, YOSHINORI ORIKASA, KENZO KAJII, TAKASHI SHOMURA, HARUO YAMAMOTO, MASAJI SEZAKI, SHIGEHARU INOUYE, SHINICHI KONDO
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1990 Volume 43 Issue 3 Pages 259-266

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Abstract

A new antibiotic SF2487 has been isolated from the culture broth of Actinomadura sp. SF2487. The structure of antibiotic SF2487 was determined by spectroscopic analyses of the sodium salt and X-ray diffraction analysis of the silver salt. The antibiotic represents a new member of polyether group antibiotics known as the acyltetronic acid type 4. The antibiotic is weakly active against Gram-positive bacteria and exhibits antiviral activity against influenza virus in vitro.

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© Japan Antibiotics Research Association
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The Journal of Antibiotics, Series A

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