Streptocidins A-D, Novel Cyclic Decapeptide Antibiotics Produced by Streptomyces sp. Tü 6071
I. Taxonomy, Fermentation, Isolation and Biological Activities
2001 Volume 54 Issue 5 Pages 428-433
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2001 Volume 54 Issue 5 Pages 428-433
Four novel cyclic homodecapetide antibiotics, Streptocidins A-D were detected in the mycelium extract of Streptomyces sp. Tü 6071 by HPLC-diode-array and HPLC-electrospraymass-spectrometry screening. The peptides which were closely related in structure to the tyrocidines and gramicidins of Bacillus brevis show antibiotic activities against Gram-positive bacteria.
