Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Insulin-stimulated Polypeptide Chain Elongation in the Soleus Muscle of Mice
Fumiaki YoshizawaAtsuya TonouchiYutaka MiuraKazumi YagasakiRyuhei Funabiki
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JOURNAL FREE ACCESS

1995 Volume 59 Issue 2 Pages 348-349

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Abstract

The effect of insulin on polypeptide chain elongation was examined in soleus muscles isolated from 18hour-fasted mice. Treatment with insulin for 1hour increased the elongation rate, which was estimated by the half-transit time. This suggests that insulin stimulated protein synthesis by modifying the elongation rate in addition to the initiation rate.

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