meta-Cleavage dioxygenase genes were isolated from the benzoate-assimilating bacteria Pseudomonas stutzeri A401 and Pseudomonas mendocina KC37. The gene products had the enzymatic activity of 2, 3-dihydroxy-biphenyl-1, 2-dioxygenase. Phylogenetic analysis based on the alignment of amino acid sequences suggests that these enzymes are distantly related to other metacleavage enzymes and may be members of a new family of extradiol dioxygenases.

This article cannot obtain the latest cited-by information.