A simple method for the purification of antiglycolipid antibody is described. Polystyrene latex beads coated with gangliotetraosylceramide (GA₁) were used as immunoadsorbent for the purification of anti-GA₁ antibody. The antibody bound to the GA₁-coated latex beads was released with 1M NaSCN solution. The glycolipidcoated latex beads seem valuable not only for the purification of antibodies but also as a tool for investigating the function of glycolipids.