Reductive cyclization of 1, 2, 3, 4-tetrahydro-6, 7-dimethoxy-1-(4, 5-dimethoxy-2-nitrophenethyl)-2-methylisoquinoline (11) with triethyl phosphite afforded 2, 3, 9, 10-tetramethoxybenz [c] acridine (12), the structure of which was identical with the sample, which was synthesized in a different route, in spectral comparisons.