Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Mechanism of Color Reaction of Aromatic Secondary and Tertiary Amines with Quinonedichlorodiimide
MASAYASU YAMAMOTOTOYOZO UNO
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1979 Volume 27 Issue 3 Pages 688-690

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Abstract

Quinonedichlorodiimide (I) reacts with aromatic secondary and tertiary amines to yield green colored compounds. The chemical structure of these colored compounds is investigated from the spectral data (infrared, ultraviolet, nuclear magnetic resonance, mass) and the chemical reactions. The color of the reaction product of I and N-ethyl-m-toluidine (II) or N, N-diethyl-m-toluidine (III) is changed mutually between green and violet by oxidation and reduction. These results and the spectral data suggest that these reactions are electrophilic displacement reactions in the ortho or para position of the alkylamino group and I reacts with II or III at the rate of 1 : 2.

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© The Pharmaceutical Society of Japan
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