Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
INFLUENCE OF THE STRUCTURE OF THE SUGAR MOIETY ON THE CYTOTOXIC AND ANTIVIRAL PROPERTIES OF SUGAR ELECTROPHILES
Jean M.J. TronchetSami ZerelliNaz DolatshahiHans Turler
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Keywords: cyanochromene
JOURNAL FREE ACCESS

1988 Volume 36 Issue 9 Pages 3722-3725

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Abstract

Blocked sugars bearing a 2-nitrovinyl, 1-cyanovinyl, 3-nitrochromen-2-yl or 4-cyano-chromen-2-yl group have been prepared. Their cytotoxicity and chemotherapeutic properties depend on the structure of the sugar moiety. Some of these compounds active against Polyoma virus constitute leads for the development of new antiviral drugs.

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© The Pharmaceutical Society of Japan
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