Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthesis and Nematocidal Activity of Diarylnonanoids Related to Malabaricones
Shinzo HOSOI, Fumiyuki KIUCHI, Norio NAKAMURA, Masaaki IMASHO, Mohammad Ahad ALI, Youhei SASAKI, Eriko TANAKA, Yoshiyuki TSUMAMOTO, Kaoru KONDO, Yoshisuke TSUDA
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Keywords: diarylnonanoid, diarylundecanoid, nematocidal activity, Toxocara canis, malabaricone, structure-activity relationship
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1999 Volume 47 Issue 1 Pages 37-43

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Abstract

Twenty diarylnonanones were synthesized and their nematocidal activity was examined. Among those, the p-hydroxy compound 16 exhibited the strongest activity comparable to the natural diarylnonanoids, malabaricones A and C. Diarylundecanoid 57 also showed appreciable activity.

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