In a population of annual chrysanthemum (Chrysanthemum coronarium L., 2n=18), two desynaptics with interchange complexes were located and their meiosis studied. They differed from one another and from the comparable normal synaptic interchange heterozygotes in the average frequency per cell of higher associations, bivalents, univalents and chiasmata. The number of chiasmata and univalents per cell showed a significantly high negative correlation. The intercell distribution of univalents and chiasmata were compared with the Poisson and binomial distribution, and they differed significantly indicating their non-random occurrence. Analysis of variance with reference to intercell and intracell variation in chiasmata revealed that the intercell variance contributed significantly more than intracell variance in causing the deviations from randomness in chiasma and univalent formation. Desynapsis is probably governed by a major factor associated with a number of modifiers exhibiting incomplete penetrance and variable expression.