Primary Epidural non-Hodgkin's Lymphoma in Clinical Stage IEA Presenting with Paraplegia and Showing Complete Recovery after Combination Therapy

Tetsuya TSUKADA; Toshiyuki OHNO; Kota TSUJI; Kenkichi KITA; Tohru KOBAYASHI; Katsumi DEGUCHI; Shigeru SHIRAKAWA

doi:10.2169/internalmedicine.31.513

Primary Epidural non-Hodgkin's Lymphoma in Clinical Stage I_EA Presenting with Paraplegia and Showing Complete Recovery after Combination Therapy

Tetsuya TSUKADA, Toshiyuki OHNO, Kota TSUJI, Kenkichi KITA, Tohru KOBAYASHI, Katsumi DEGUCHI, Shigeru SHIRAKAWA

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Keywords: spinal-epidural tumor, malignant lymphoma, spinal cord compression

JOURNAL FREE ACCESS

1992 Volume 31 Issue 4 Pages 513-515

DOI https://doi.org/10.2169/internalmedicine.31.513

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Abstract

A 70-year-old man was admitted to our hospital because of paraplegia. A spinal epidural tumor (Th VII-XI) was diagnosed by magnetic resonance imaging and resected. Histological examination of the tumor showed non-Hodgkin's lymphoma of the diffuse large cell type (Lymphoma Study Group classification), with a B cell phenotype. The clinical stage was I_EA by the Ann Arbor classification. Radiation therapy of the involved field was performed (total dose : 40Gy), followed by six courses of modified cyclophosphamide, adriamycine, vincristine, prednisolone (CHOP) therapy. He was discharged walking unaided 10 months later and has shown no evidence of relapse in the 26 months since discharge.
(Internal Medicine 31 : 513-515, 1992)

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